Overview
SCIENTIFIC SCORE
Moderately Effective
Based on 3 Researches
8.3
USERS' SCORE
Good
Based on 38 Reviews
8.4
Supplement Facts
Serving Size: 1 Vegetarian Tablet
Amount Per Serving
%DV
Vitamin C (as Ester-C® Calcium Ascorbate)
1,000 mg (1 g)
1,111%
Calcium (as Ester-C® Calcium Ascorbate)
110 mg
8%
Citrus Bioflavonoids ComplexCitrus Bioflavonoids (Citrus sinensis) (fruit), Sweet Orange, Tangerine, Lime, Lemon, Acerola, Rutin, Hesperidin Complex (Citrus spp.) (fruit), Naturally Occurring Vitamin C Metabolites
200 mg
**
Top Medical Research Studies
9
We investigated how an ascorbic acid-based solution could help treat recurrent cold sores, also known as mucocutaneous herpes. This study was carefully designed as a randomized, double-blind, placebo-controlled trial, which helps ensure the results are reliable and trustworthy.
Participants used a strong solution of Ascoxal, rich in vitamin C, applied to their cold sores multiple times on the first day of the outbreak. We monitored various symptoms daily, including the severity of scabs, redness, and blisters, comparing the experiences of those using the vitamin C solution to a placebo group.
Our findings were promising: the active treatment resulted in fewer days with scabbing and less severe symptoms overall. Moreover, those using the vitamin C solution showed reduced persistence of scabs compared to the placebo group, along with a lower frequency of detected herpes virus after treatment.
In conclusion, this brief course of vitamin C treatment appears to have significant clinical benefits against cold sores, opening the door for future research on more extensive and frequent treatment regimes.
Participants used a strong solution of Ascoxal, rich in vitamin C, applied to their cold sores multiple times on the first day of the outbreak. We monitored various symptoms daily, including the severity of scabs, redness, and blisters, comparing the experiences of those using the vitamin C solution to a placebo group.
Our findings were promising: the active treatment resulted in fewer days with scabbing and less severe symptoms overall. Moreover, those using the vitamin C solution showed reduced persistence of scabs compared to the placebo group, along with a lower frequency of detected herpes virus after treatment.
In conclusion, this brief course of vitamin C treatment appears to have significant clinical benefits against cold sores, opening the door for future research on more extensive and frequent treatment regimes.
Read More
8
We conducted a clinical pilot study to evaluate the effects of a combination treatment of lignin—a substance derived from pine cones—mixed with vitamin C on cold sores caused by the herpes simplex virus type 1 (HSV-1). Our study included 48 healthy participants, ranging from 4 to 61 years old, who had active lesions of HSV-1.
Participants received a daily dose of the lignin-ascorbic acid treatment for one month. Notably, those who began the treatment within the first 48 hours after the onset of symptoms did not develop typical cold sore lesions. For others who started later, we observed a shorter duration of cold sores and less severe symptoms compared to their previous outbreaks.
Many participants reported a reduction in both the severity and frequency of their cold sore episodes during treatment. Although the results suggest some benefits of this combination treatment, it’s important to note that vitamin C was part of the blend, making it challenging to evaluate its individual effect on cold sores directly.
Thus, while the combination of lignin and vitamin C appears promising for preventing and treating HSV-1 infection, further studies isolating vitamin C's effects would be helpful to understand its specific role in managing cold sores.
Participants received a daily dose of the lignin-ascorbic acid treatment for one month. Notably, those who began the treatment within the first 48 hours after the onset of symptoms did not develop typical cold sore lesions. For others who started later, we observed a shorter duration of cold sores and less severe symptoms compared to their previous outbreaks.
Many participants reported a reduction in both the severity and frequency of their cold sore episodes during treatment. Although the results suggest some benefits of this combination treatment, it’s important to note that vitamin C was part of the blend, making it challenging to evaluate its individual effect on cold sores directly.
Thus, while the combination of lignin and vitamin C appears promising for preventing and treating HSV-1 infection, further studies isolating vitamin C's effects would be helpful to understand its specific role in managing cold sores.
Read More
8
We evaluated the effectiveness of a water-soluble complex combining bioflavonoids and ascorbic acid, which is commonly known as vitamin C, for treating cold sores caused by recurrent herpes labialis. The study involved 50 episodes of cold sores, with patients receiving different dosages of the vitamin C and bioflavonoid combination, while others were given a lactose placebo.
The regimen was followed for three days after participants felt the initial symptoms. We noted that the combination appeared to reduce the formation of blisters and helped maintain the integrity of the vesicular membrane. The best results came when treatment started during the early warning signs of an outbreak, leading to symptom relief in an average of about 4.2 days with the lower dosage.
Importantly, throughout the study, no adverse reactions were reported by participants. Although the combination product shows promise, it was difficult to isolate the specific impact of vitamin C alone due to its synergy with bioflavonoids.
The regimen was followed for three days after participants felt the initial symptoms. We noted that the combination appeared to reduce the formation of blisters and helped maintain the integrity of the vesicular membrane. The best results came when treatment started during the early warning signs of an outbreak, leading to symptom relief in an average of about 4.2 days with the lower dosage.
Importantly, throughout the study, no adverse reactions were reported by participants. Although the combination product shows promise, it was difficult to isolate the specific impact of vitamin C alone due to its synergy with bioflavonoids.
Read More
Most Useful Reviews
9
Effective cold prevention
4 people found this helpful
Very effective; I take it daily and haven’t had a cold in the past six months. It's also great for managing stress and boosting energy.
Read More
9
Quick cold relief
2 people found this helpful
Excellent vitamin C with high bioavailability. It doesn’t irritate my stomach, and as soon as I sense a cold, I take it, and symptoms recede quickly, even during Covid recovery.
Read More
9
Prevents flu effectively
2 people found this helpful
We’ve regularly had this over winter, and nobody fell ill with the flu! Now, at the first signs of illness, we take 1 or 2 tablets, and colds are kept at bay. It’s a life-saver!
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 3 Researches
8.3
- All Researches
9
We investigated how an ascorbic acid-based solution could help treat recurrent cold sores, also known as mucocutaneous herpes. This study was carefully designed as a randomized, double-blind, placebo-controlled trial, which helps ensure the results are reliable and trustworthy.
Participants used a strong solution of Ascoxal, rich in vitamin C, applied to their cold sores multiple times on the first day of the outbreak. We monitored various symptoms daily, including the severity of scabs, redness, and blisters, comparing the experiences of those using the vitamin C solution to a placebo group.
Our findings were promising: the active treatment resulted in fewer days with scabbing and less severe symptoms overall. Moreover, those using the vitamin C solution showed reduced persistence of scabs compared to the placebo group, along with a lower frequency of detected herpes virus after treatment.
In conclusion, this brief course of vitamin C treatment appears to have significant clinical benefits against cold sores, opening the door for future research on more extensive and frequent treatment regimes.
Participants used a strong solution of Ascoxal, rich in vitamin C, applied to their cold sores multiple times on the first day of the outbreak. We monitored various symptoms daily, including the severity of scabs, redness, and blisters, comparing the experiences of those using the vitamin C solution to a placebo group.
Our findings were promising: the active treatment resulted in fewer days with scabbing and less severe symptoms overall. Moreover, those using the vitamin C solution showed reduced persistence of scabs compared to the placebo group, along with a lower frequency of detected herpes virus after treatment.
In conclusion, this brief course of vitamin C treatment appears to have significant clinical benefits against cold sores, opening the door for future research on more extensive and frequent treatment regimes.
Read More
8
We conducted a clinical pilot study to evaluate the effects of a combination treatment of lignin—a substance derived from pine cones—mixed with vitamin C on cold sores caused by the herpes simplex virus type 1 (HSV-1). Our study included 48 healthy participants, ranging from 4 to 61 years old, who had active lesions of HSV-1.
Participants received a daily dose of the lignin-ascorbic acid treatment for one month. Notably, those who began the treatment within the first 48 hours after the onset of symptoms did not develop typical cold sore lesions. For others who started later, we observed a shorter duration of cold sores and less severe symptoms compared to their previous outbreaks.
Many participants reported a reduction in both the severity and frequency of their cold sore episodes during treatment. Although the results suggest some benefits of this combination treatment, it’s important to note that vitamin C was part of the blend, making it challenging to evaluate its individual effect on cold sores directly.
Thus, while the combination of lignin and vitamin C appears promising for preventing and treating HSV-1 infection, further studies isolating vitamin C's effects would be helpful to understand its specific role in managing cold sores.
Participants received a daily dose of the lignin-ascorbic acid treatment for one month. Notably, those who began the treatment within the first 48 hours after the onset of symptoms did not develop typical cold sore lesions. For others who started later, we observed a shorter duration of cold sores and less severe symptoms compared to their previous outbreaks.
Many participants reported a reduction in both the severity and frequency of their cold sore episodes during treatment. Although the results suggest some benefits of this combination treatment, it’s important to note that vitamin C was part of the blend, making it challenging to evaluate its individual effect on cold sores directly.
Thus, while the combination of lignin and vitamin C appears promising for preventing and treating HSV-1 infection, further studies isolating vitamin C's effects would be helpful to understand its specific role in managing cold sores.
Read More
8
We evaluated the effectiveness of a water-soluble complex combining bioflavonoids and ascorbic acid, which is commonly known as vitamin C, for treating cold sores caused by recurrent herpes labialis. The study involved 50 episodes of cold sores, with patients receiving different dosages of the vitamin C and bioflavonoid combination, while others were given a lactose placebo.
The regimen was followed for three days after participants felt the initial symptoms. We noted that the combination appeared to reduce the formation of blisters and helped maintain the integrity of the vesicular membrane. The best results came when treatment started during the early warning signs of an outbreak, leading to symptom relief in an average of about 4.2 days with the lower dosage.
Importantly, throughout the study, no adverse reactions were reported by participants. Although the combination product shows promise, it was difficult to isolate the specific impact of vitamin C alone due to its synergy with bioflavonoids.
The regimen was followed for three days after participants felt the initial symptoms. We noted that the combination appeared to reduce the formation of blisters and helped maintain the integrity of the vesicular membrane. The best results came when treatment started during the early warning signs of an outbreak, leading to symptom relief in an average of about 4.2 days with the lower dosage.
Importantly, throughout the study, no adverse reactions were reported by participants. Although the combination product shows promise, it was difficult to isolate the specific impact of vitamin C alone due to its synergy with bioflavonoids.
Read More
User Reviews
USERS' SCORE
Good
Based on 38 Reviews
8.4
- All Reviews
- Positive Reviews
- Negative Reviews
9
Effective cold prevention
4 people found this helpful
Very effective; I take it daily and haven’t had a cold in the past six months. It's also great for managing stress and boosting energy.
Read More
9
Quick cold relief
2 people found this helpful
Excellent vitamin C with high bioavailability. It doesn’t irritate my stomach, and as soon as I sense a cold, I take it, and symptoms recede quickly, even during Covid recovery.
Read More
9
Prevents flu effectively
2 people found this helpful
We’ve regularly had this over winter, and nobody fell ill with the flu! Now, at the first signs of illness, we take 1 or 2 tablets, and colds are kept at bay. It’s a life-saver!
Read More
9
Enhanced immune response
2 people found this helpful
This is the best available! This vitamin has no acid and lasts in the body for 24 hours. When I start to feel unwell, I take 3 tablets as advised by my doctor, and my body resists viruses effectively. Taking one tablet daily helps in avoiding constant colds.
Read More
9
Protects from colds
2 people found this helpful
In my opinion, the best vitamin C! After reading about Ester C a few years back, I began using it regularly, and my whole family of six does too. I’m certain that, over the past three years, not a single family member has caught even a minor cold, thanks to our regular consumption of high-quality vitamin C.
Read More
Frequently Asked Questions
9
Immediate cold relief
1 people found this helpful
This vitamin was a timely purchase! My daughter caught a cold at her new job, and I urged her to take a shock dose of it. Remarkably, she felt symptom-free the very next day. She was once skeptical about supplements, but now believes in their efficacy. Plus, it causes no stomach discomfort.
9
Decreases cold duration
8 people found this helpful
At the first signs of a cold, I take a pill in the morning and evening after meals for no more than three days. I ensure to drink ample water. While I do experience a couple of days of illness, with this treatment, colds last only three days, not the usual 5-7. My skin appears better with regular use.
9
Strengthened immune system
Very effective vitamins! When I caught a cold, I started taking them straight away for three days, and thankfully, I had no cold symptoms. It's crucial to begin as soon as you feel the first signs of a cold for them to work. The formula is gentle on the stomach and boosts the immune system. I took them on my doctor's recommendation. If you find my post helpful, please give it a like.
9
Effective cold prevention
4 people found this helpful
Very effective; I take it daily and haven’t had a cold in the past six months. It's also great for managing stress and boosting energy.
9
Prevents flu effectively
2 people found this helpful
We’ve regularly had this over winter, and nobody fell ill with the flu! Now, at the first signs of illness, we take 1 or 2 tablets, and colds are kept at bay. It’s a life-saver!
9
Seasonal cold prevention
6 people found this helpful
This is a brilliant product! I've taken it consistently for three years now, having tried other kinds of vitamin C. This is by far the best, causing no unpleasant sensations. I take 3g daily and find my family hardly catches colds anymore. I continually recommend it to friends, as Vitamin C is an essential daily antioxidant!
9
Relieves cold signs
3 people found this helpful
Best vitamin ever! Ester-C is unparalleled in bioavailability! It’s known that ascorbic acid is ineffective; it’s wise to invest in quality vitamins like this to boost immunity! A life hack: if cold symptoms arise, take two vitamins (with zinc ideally), and you’ll recover in no time! I've tested it myself and absolutely recommend it!
9
Accelerates recovery
1 people found this helpful
Super! Whenever I start to feel unwell, I take a pill of this vitamin, sometimes up to three per day during a cold. It helps to significantly speed up recovery. This should always be readily available at home.
9
Enhanced immune response
2 people found this helpful
This is the best available! This vitamin has no acid and lasts in the body for 24 hours. When I start to feel unwell, I take 3 tablets as advised by my doctor, and my body resists viruses effectively. Taking one tablet daily helps in avoiding constant colds.
8
We conducted a clinical pilot study to evaluate the effects of a combination treatment of lignin—a substance derived from pine cones—mixed with vitamin C on cold sores caused by the herpes simplex virus type 1 (HSV-1). Our study included 48 healthy participants, ranging from 4 to 61 years old, who had active lesions of HSV-1.
Participants received a daily dose of the lignin-ascorbic acid treatment for one month. Notably, those who began the treatment within the first 48 hours after the onset of symptoms did not develop typical cold sore lesions. For others who started later, we observed a shorter duration of cold sores and less severe symptoms compared to their previous outbreaks.
Many participants reported a reduction in both the severity and frequency of their cold sore episodes during treatment. Although the results suggest some benefits of this combination treatment, it’s important to note that vitamin C was part of the blend, making it challenging to evaluate its individual effect on cold sores directly.
Thus, while the combination of lignin and vitamin C appears promising for preventing and treating HSV-1 infection, further studies isolating vitamin C's effects would be helpful to understand its specific role in managing cold sores.
Participants received a daily dose of the lignin-ascorbic acid treatment for one month. Notably, those who began the treatment within the first 48 hours after the onset of symptoms did not develop typical cold sore lesions. For others who started later, we observed a shorter duration of cold sores and less severe symptoms compared to their previous outbreaks.
Many participants reported a reduction in both the severity and frequency of their cold sore episodes during treatment. Although the results suggest some benefits of this combination treatment, it’s important to note that vitamin C was part of the blend, making it challenging to evaluate its individual effect on cold sores directly.
Thus, while the combination of lignin and vitamin C appears promising for preventing and treating HSV-1 infection, further studies isolating vitamin C's effects would be helpful to understand its specific role in managing cold sores.
9
We investigated how an ascorbic acid-based solution could help treat recurrent cold sores, also known as mucocutaneous herpes. This study was carefully designed as a randomized, double-blind, placebo-controlled trial, which helps ensure the results are reliable and trustworthy.
Participants used a strong solution of Ascoxal, rich in vitamin C, applied to their cold sores multiple times on the first day of the outbreak. We monitored various symptoms daily, including the severity of scabs, redness, and blisters, comparing the experiences of those using the vitamin C solution to a placebo group.
Our findings were promising: the active treatment resulted in fewer days with scabbing and less severe symptoms overall. Moreover, those using the vitamin C solution showed reduced persistence of scabs compared to the placebo group, along with a lower frequency of detected herpes virus after treatment.
In conclusion, this brief course of vitamin C treatment appears to have significant clinical benefits against cold sores, opening the door for future research on more extensive and frequent treatment regimes.
Participants used a strong solution of Ascoxal, rich in vitamin C, applied to their cold sores multiple times on the first day of the outbreak. We monitored various symptoms daily, including the severity of scabs, redness, and blisters, comparing the experiences of those using the vitamin C solution to a placebo group.
Our findings were promising: the active treatment resulted in fewer days with scabbing and less severe symptoms overall. Moreover, those using the vitamin C solution showed reduced persistence of scabs compared to the placebo group, along with a lower frequency of detected herpes virus after treatment.
In conclusion, this brief course of vitamin C treatment appears to have significant clinical benefits against cold sores, opening the door for future research on more extensive and frequent treatment regimes.
8
We evaluated the effectiveness of a water-soluble complex combining bioflavonoids and ascorbic acid, which is commonly known as vitamin C, for treating cold sores caused by recurrent herpes labialis. The study involved 50 episodes of cold sores, with patients receiving different dosages of the vitamin C and bioflavonoid combination, while others were given a lactose placebo.
The regimen was followed for three days after participants felt the initial symptoms. We noted that the combination appeared to reduce the formation of blisters and helped maintain the integrity of the vesicular membrane. The best results came when treatment started during the early warning signs of an outbreak, leading to symptom relief in an average of about 4.2 days with the lower dosage.
Importantly, throughout the study, no adverse reactions were reported by participants. Although the combination product shows promise, it was difficult to isolate the specific impact of vitamin C alone due to its synergy with bioflavonoids.
The regimen was followed for three days after participants felt the initial symptoms. We noted that the combination appeared to reduce the formation of blisters and helped maintain the integrity of the vesicular membrane. The best results came when treatment started during the early warning signs of an outbreak, leading to symptom relief in an average of about 4.2 days with the lower dosage.
Importantly, throughout the study, no adverse reactions were reported by participants. Although the combination product shows promise, it was difficult to isolate the specific impact of vitamin C alone due to its synergy with bioflavonoids.
References
- Lopez BS, Yamamoto M, Utsumi K, Aratsu C, Sakagami H. A clinical pilot study of lignin--ascorbic acid combination treatment of herpes simplex virus. In Vivo. 2009;23:1011.
- Hovi T, Hirvimies A, Stenvik M, Vuola E, Pippuri R. Topical treatment of recurrent mucocutaneous herpes with ascorbic acid-containing solution. Antiviral Res. 1995;27:263.
- Terezhalmy GT, Bottomley WK, Pelleu GB. The use of water-soluble bioflavonoid-ascorbic acid complex in the treatment of recurrent herpes labialis. Oral Surg Oral Med Oral Pathol. 1978;45:56.
